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Recruiting Trials

Research Area
Study Name
Basic Eligibility
Doctors Referral
Participant Enquiry

Cardiology

Research Area:
Cardiology
Stenosis
Study Name:
DynamX Bioadaptor
Basic Eligibility:
Aged 20 or older, myocardial ischemia, able to undergo PTCA, stenting and CABG
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients at Middlemore Hospital.

Research Area:
Cardiology
Acute Coronary Syndrome
Study Name:
AEGIS-II (CSL112_3001)
Basic Eligibility:
Type 1 Myocardial infarction
Have at least two coronary artery territories of disease > 50%
Be on treatment for Diabetes
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients currently an inpatient at Middlemore Hospital.

Gastroenterology/Hepatology

Research Area:
Gastroenterology/Hepatology
Non-alcoholic Steatohepatitis
Study Name:
MK-3655-001-00 (NASH)
Basic Eligibility:
Male or postmenopausal female, aged 18-80 years old, diagnosed Nonalcoholic Steatohepatitis, no other chronic liver disease
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Gastroenterology/Hepatology
Non-alcoholic Fatty Liver Disease
Study Name:
MK-6024 NAFLD
Basic Eligibility:
Aged between 18-70 years old
Diagnosis of Non-alcoholic Fatty Liver Disease
Have a BMI between 25 to 50 kg/m2
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Gastroenterology/Hepatology
Ulcerative colitis
Study Name:
AVOGADRO-UC (Ulcerative colitis)
Basic Eligibility:
Age less than 65 years, have diagnosed ulcerative colitis and experiencing increase in daily stool frequency and/or rectal bleeding, no allergy to antibiotic vancomycin, willing to undergo two colonoscopy procedures as part of the study (3 months apart)
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Gastroenterology/Hepatology
Chronic Hepatitis B
Study Name:
BRII-179-835-001, DCR-HBVS-101, GS-US-493-5342, VIR (VIR-2218)
Basic Eligibility:
Aged 18 to 65
Chronic Hepatitis B infection
On stable NUC treatment (e.g Entecavir orTenofovir)
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Haematology

Research Area:
Haematology
Multiple Myeloma
Study Name:
BGB-11417-105
Basic Eligibility:
Age ≥ 18
Diagnosed with Relapsed or Refractory Multiple Myeloma
No long-term use of Prednisone
Doctors Referral:
Refer a Patient
Participant Enquiry:
Ask your Haematologist if this is right for you.

Research Area:
Haematology
Multiple Myeloma
Study Name:
FRAIL-M
Basic Eligibility:
Age ≥ 18
Newly diagnosed multiple myeloma
Ineligible for autologous stem cell transplant
No prior treatment for multiple myeloma except localised radiotherapy or a short course of steroids
Doctors Referral:
Refer a Patient
Participant Enquiry:
Ask your Haematologist if this is right for you.

Research Area:
Haematology
Myelodysplastic Syndrome (MDS)
Study Name:
KER050 (Anemia in MDS)
Basic Eligibility:
Age ≥ 18
Diagnosed with Myelodysplastic Syndrome (MDS)
Anemia
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Haematology
Multiple Myeloma
Study Name:
DREAMM8
Basic Eligibility:
Age ≥ 18
Diagnosed with Relapsed or Refractory Multiple Myeloma.
Doctors Referral:
Refer a Patient
Participant Enquiry:
Ask your Haematologist if this is right for you.

Research Area:
Haematology
Essential Thrombocythemia
Study Name:
IMG-7289-CTP-201
Basic Eligibility:
Age ≥ 18
Diagnosis of Essential Thrombocythemia
Failure of standard therapy, e.g. Hydroxyurea
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Infectious Diseases

Research Area:
Infectious Diseases
Viral Respiratory Disease
Study Name:
SHIVERS
Basic Eligibility:
Viral respiratory disease
Acute presentation to Middlemore Emergency Department or Intensive care unit
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients with acute presentation at Middlemore Hospital.

Research Area:
Infectious Diseases
Rheumatic Fever
Study Name:
Start
Basic Eligibility:
Aged between 5 - 14 years
Newly diagnosed with Acute rheumatic fever
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients currently an inpatient at Middlemore Hospital.

Research Area:
Infectious Diseases
Respiratory Syncytial Virus
Study Name:
RSV study
Basic Eligibility:
Healthy woman aged between 18 and 49 years of age
Pregnant with no known increased risk for complications
Singleton pregnancy
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Infectious Diseases
Staph Aureus infection
Study Name:
Staph Aureus Vaccine
Basic Eligibility:
Are 18-50 years of age.
Have a current/recent skin infection.
No ongoing illness or history of serious chronic/progressive disease.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Plastics and Burns

Research Area:
Plastics and Burns
Wound healing
Study Name:
NPWT
Basic Eligibility:
≥ 18 years of age, undergoing a surgical procedure resulting in a closed approximately linear incision
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients at Middlemore Hospital.

Renal

Research Area:
Renal
Hypertension
Study Name:
Polypill
Basic Eligibility:
Aged 18 years or older, hypertensive, no more than 3 current blood-pressure lowering medications.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Renal
IgA Neuropathy
Study Name:
The Align Study
Basic Eligibility:
Aged 18 or older, diagnosis of IgAN, on a stable dose of an ACE inhibitor or ARB / unable to tolerate this therapy.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Respiratory

Research Area:
Respiratory
Bronchiectasis
Study Name:
ASPEN
Basic Eligibility:
Aged 18-85, diagnosed non-cystic fibrosis bronchiectasis, two or more exacerbations in the past 12 months.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Respiratory
Chronic obstructive pulmonary disease
Study Name:
PACE
Basic Eligibility:
Aged between 40 and 85 years
Diagnosed with COPD
A history of cardiovascular disease, including heart failure, ischaemic heart disease, tachyarrhythmias, and hypertension
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Respiratory
Bronchiectasis
Study Name:
Resveratrol
Basic Eligibility:
Aged over 18 years
Confirmed diagnosis of bronchiectasis within 5 years
Pulmonary exacerbation requiring antibiotics in the past 12 months
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Rheumatology

Research Area:
Rheumatology
Ankylosing Spondylitis/Axial Spondyloarthritis
Study Name:
Ankylosing Spondylitis/Axial Spondyloarthritis
Basic Eligibility:
Aged 18 years or older
Diagnosis of Ankylosing Spondylitis or Axial Spondyloarthritis
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Rheumatology
Polymyalgia Rheumatica
Study Name:
HUBBLE PMR
Basic Eligibility:
Aged between 50-80.
Have been diagnosed with Polymyalgia Rheumatica (PMR).
Have experienced improvement in PMR symptoms with Prednisone.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Rheumatology
Giant Cell Arthritis
Study Name:
Select - GCA (M16-852)
Basic Eligibility:
Age 50 or over
Diagnosed Giant Cell Arthritis
Headache, jaw pain, vision loss
Shoulder and/or hip pain
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Spinal Unit

Research Area:
Spinal Unit
Wound healing
Study Name:
FPH Spinal
Basic Eligibility:
Aged 22 and older, undergoing 1 or 2 level spinal decompression
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients at Middlemore Hospital.

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About Us

Middlemore Clinical Trials is a fully integrated research unit based at Middlemore Hospital in the heart of South Auckland, New Zealand.

We perform biopharma and medical device clinical trials in partnership with all hospital departments focusing on the diseases and Long term health conditions that affect our diverse community.

 

 

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