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Recruiting Trials

Research Area
Study Name
Basic Eligibility
Doctors Referral
Participant Enquiry

Research Area:
Viral Respiratory Disease
Study Name:
SHIVERS
Basic Eligibility:
Viral respiratory disease
Acute presentation to Middlemore Emergency Department or Intensive care unit
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients with acute presentation at Middlemore Hospital.

Research Area:
Rheumatic Fever
Study Name:
Start
Basic Eligibility:
Aged between 5 - 14 years
Newly diagnosed with Acute rheumatic fever
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients currently an inpatient at Middlemore Hospital.

Cardiology

Research Area:
Cardiology
Stenosis
Study Name:
DynamX Bioadaptor
Basic Eligibility:
Aged 20 or older, myocardial ischemia, able to undergo PTCA, stenting and CABG
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients at Middlemore Hospital.

Research Area:
Cardiology
Acute Coronary Syndrome
Study Name:
AEGIS-II (CSL112_3001)
Basic Eligibility:
Type 1 Myocardial infarction
Have at least two coronary artery territories of disease > 50%
Be on treatment for Diabetes
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients currently an inpatient at Middlemore Hospital.

Diabetes

Research Area:
Diabetes
Diabetic Kidney Disease
Study Name:
Type 2 Diabetes / Chronic Kidney Disease
Basic Eligibility:
Are you aged ≥18 ≤79?
Have been receiving stable treatment for your diabetes and diabetic kidney disease for the past 3 months?
Are you able to participate in a study for up to 26 weeks?
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Diabetes
Type 2 Diabetes
Study Name:
DeLIVER
Basic Eligibility:
Are you aged between 22 and 70?
Have you been diagnosed with Type 2 Diabetes?
Are you on a consistent drug regimen of Metformin or Metformin/Vildagliptin only?
Do you have a waist circumference ≥102 cm (male) and ≥88 cm (female)?
Have you been diagnosed with hypertension:SBP ≥140 mmHg OR on ≤2 hypertension medications with SBP ≥130 mmHg?
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Diabetes
Type 2 Diabetes/Obesity
Study Name:
Adolescent Bariatric Study
Basic Eligibility:
Aged between 15 years 9 months and 18
Obesity with a BMI >35
Diagnosed with either pre-diabetes or type 2 diabetes
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Gastroenterology/Hepatology

Research Area:
Gastroenterology/Hepatology
Chronic Hepatitis B
Study Name:
BRII-179-835-001
Basic Eligibility:
Aged between 18-60
Chronic Hepatitis B infection
Taking tenofovir or entecavir for at least 12 months
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Gastroenterology/Hepatology
Chronic Hepatitis B
Study Name:
DCR-HBVS-101, GS-US-493-5342, Penguin, VIR (VIR-2218)
Basic Eligibility:
Age 18 to 65
Chronic Hepatitis B infection
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Gastroenterology/Hepatology
Chronic Hepatitis B
Study Name:
Piranga [WV41073 (CHB)]
Basic Eligibility:
Aged 18 to 65
Chronic Hepatitis B infection
On stable NUC treatment (e.g Entecavir orTenofovir)
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Haematology

Research Area:
Haematology
Follicular Lymphoma
Study Name:
FL212 (BGB-3111-212)
Basic Eligibility:
Age over 18 years
Diagnosed Follicular Lymphoma
Doctors Referral:
Refer a Patient
Participant Enquiry:
Ask your doctor if this is right for you.

Research Area:
Haematology
Myelodysplastic Syndrome (MDS)
Study Name:
KER050 (Anemia in MSD)
Basic Eligibility:
Age ≥ 18
Diagnosed with Myelodysplastic Syndrome (MDS)
Anemia
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Haematology
Myelofibrosis
Study Name:
MOMENTUM (SRA-MMB-301)
Basic Eligibility:
Age over 18
Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post Essential Thrombocythemia Myelofibrosis
Previously treaded with Ruxolitinib
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Haematology
Lymphoma - Non-Hodgkins
Study Name:
B-MIND
Basic Eligibility:
Aged 18 years or older
Confirmed diagnosis of DLBCL
Doctors Referral:
Refer a Patient
Participant Enquiry:
Ask your doctor if this is right for you.

Research Area:
Haematology
Essential Thrombocythemia
Study Name:
IMG-7289-CTP-201
Basic Eligibility:
Age ≥ 18
Diagnosis of Essential Thrombocythemia
Failure of standard therapy, e.g. Hydroxyurea
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Neonatal

Research Area:
Neonatal
Neonatal care
Study Name:
PAEAN
Basic Eligibility:
Infants born at or more than 35 weeks
Indication of perinatal depression
Moderate to severe encephalopathy
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible premature infants at delivery.

Plastics and Burns

Research Area:
Plastics and Burns
Wound healing
Study Name:
NPWT
Basic Eligibility:
≥ 18 years of age, undergoing a surgical procedure resulting in a closed approximately linear incision
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients at Middlemore Hospital.

RSV

Research Area:
RSV
Respiratory syncytial virus
Study Name:
Melody
Basic Eligibility:
Baby born after October 2020, at 35 weeks gestation or above.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
RSV
Respiratory syncytial virus
Study Name:
RSV OA
Basic Eligibility:
60 years and older, healthy or medically stable, no flu vaccine in the last 6 months.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
RSV
Respiratory syncytial virus
Study Name:
RSV study
Basic Eligibility:
Healthy woman aged between 18 and 49 years of age?
Pregnant with no known increased risk for complications?
Singleton pregnancy?
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Renal

Research Area:
Renal
Hypertension
Study Name:
Polypill
Basic Eligibility:
Aged 18 years or older, hypertensive, no more than 3 current blood-pressure lowering medications.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Renal
IgA Neuropathy
Study Name:
The Align Study
Basic Eligibility:
Aged 18 or older, diagnosis of IgAN, on a stable dose of an ACE inhibitor or ARB / unable to tolerate this therapy.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Respiratory

Research Area:
Respiratory
Bronchiectasis
Study Name:
ASPEN
Basic Eligibility:
Aged 18-85, diagnosed non-cystic fibrosis bronchiectasis, two or more exacerbations in the past 12 months.
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Respiratory
Chronic obstructive pulmonary disease
Study Name:
PACE
Basic Eligibility:
Aged between 40 and 85 years
Diagnosed with COPD
A history of cardiovascular disease, including heart failure, ischaemic heart disease, tachyarrhythmias, and hypertension
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Respiratory
Bronchiectasis
Study Name:
Resveratrol
Basic Eligibility:
Aged over 18 years
Confirmed diagnosis of bronchiectasis within 5 years
Pulmonary exacerbation requiring antibiotics in the past 12 months
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Rheumatology

Research Area:
Rheumatology
Ankylosing Spondylitis/Axial Spondyloarthritis
Study Name:
Ankylosing Spondylitis/Axial Spondyloarthritis
Basic Eligibility:
Aged 18 years or older
Diagnosis of Ankylosing Spondylitis or Axial Spondyloarthritis
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Research Area:
Rheumatology
Giant Cell Arthritis
Study Name:
Select - GCA (M16-852)
Basic Eligibility:
Age 50 or over
Diagnosed Giant Cell Arthritis
Headache, jaw pain, vision loss
Shoulder and/or hip pain
Doctors Referral:
Refer a Patient
Participant Enquiry:
See if you qualify

Spinal Unit

Research Area:
Spinal Unit
Wound healing
Study Name:
FPH Spinal
Basic Eligibility:
Aged 22 and older, undergoing 1 or 2 level spinal decompression
Doctors Referral:
Refer a Patient
Participant Enquiry:
Trial for eligible patients at Middlemore Hospital.

About Us

Middlemore Clinical Trials (MMCT) is New Zealand's largest clinical trials unit, based in one of New Zealand's largest and leading hospitals. We offer world-class facilities, experienced and well trained staff and a fully integrated research unit. 

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