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Recruiting Trials

Clinical Lipidology

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Clinical Lipidology

Familial Chylomicronemia Syndrome

KEPLER

Age ≥ 18
Fasting triglyceride level ≥10 mmol/L
Diagnosed with familial chylomicronemia syndrome

See if you qualify

Gastroenterology / Hepatology

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Gastroenterology / Hepatology

Non-alcoholic Steatohepatitis (NASH)

PROXYMO II

Aged between 18 and 75 years old.
Diagnosed with Non-alcoholic Steatohepatitis (NASH).

See if you qualify

Chronic Hepatitis B

MARCH (VIR-2218)

Age 18 - 65
Chronic hepatitis B infection
On stable NUC therapy (e.g. entecavir or tenofovir)

See if you qualify

Chronic Hepatitis B

Piranga

Age 18 - 65
Chronic hepatitis B infection
On stable NUC therapy (e.g. entecavir or tenofovir alafenamide/disoproxil fumarate)

See if you qualify

Haematology

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Haematology

Multiple Myeloma

BGB-11417-105

Age ≥ 18
Diagnosed with relapsed or refractory multiple myeloma
No long-term use of prednisone

By Specialist Referral
Ask your Haematologist if this is right for you.

Multiple Myeloma

FRAIL-M

Age ≥ 18
Newly diagnosed multiple myeloma
Ineligible for autologous stem cell transplant
No prior treatment for multiple myeloma except localised radiotherapy or a short course of steroids

By Specialist Referral
Ask your Haematologist if this is right for you.

Myelodysplastic Syndrome

KER050 (Anemia in MDS)

Age ≥ 18
Diagnosed with myelodysplastic syndrome (MDS)
Has anemia

See if you qualify

Myelofibrosis

TRANSFORM-1

Age ≥ 18
Diagnosed primary or secondary myelofibrosis
Has splenomegaly

By Specialist Referral
Ask your Haematologist if this is right for you.

Infectious Diseases and Vaccines

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Infectious Diseases and Vaccines

Staphylococcus Aureus Infection

SNAP

Staphylococcus aureus bloodstream infection
Admitted to hospital

By Specialist Referral
Trial for eligible patients at Middlemore Hospital.

Urinary Tract Infection

E.mbrace

Age ≥ 60
History of urinary tract infection in past 2 years

See if you qualify

COVID-19 Infection

ASCOT

Age ≥ 18
Admitted to an acute-care hospital
Confirmed SARS-CoV-2 by nucleic acid testing in the 14 days prior to randomisation

By Specialist Referral
Trial for eligible patients at Middlemore Hospital.

Oncology

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Oncology

Colorectal Adenoma

The OSCAR Trial

Advanced colorectal adenoma at first colonoscopy in the National Bowel Screening Programme
No residual colorectal adenomas
Next colonoscopy planned within 5 years

By Specialist Referral
Trial for eligible patients at Middlemore Hospital.

Indigenous (Australian Aboriginal and/or Torres Strait Islander; or New Zealander Maori and/or Pacific Islander)
Hospitalised with an ALRI (bronchiolitis or pneumonia)
Required oxygen or respiratory support at any point of illness (including transfer and in the community) OR fluid support (NG or IV) OR recurrent admission within 3 months
Aged ≥ 3 months

By Specialist Referral
Trial for eligible patients at Kidz First, Middlemore Hospital.

Plastics and Burns

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Plastics and Burns

Wound healing

NPWT

Age ≥ 18
Be undergoing a surgical procedure resulting in a closed approximately linear incision

By Specialist Referral
Trial for eligible patients at Middlemore Hospital.

Renal

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Renal

End Stage Kidney Disease (ESKD)

Phosphate Trial

Age ≥ 45 or ≥ 18 years with diabetes
ESKD treated with haemodialysis, or peritoneal dialysis, for at
least 3 months
Prescribed at least one phosphate-lowering medication at any
dose

By Specialist Referral
Trial for eligible patients at Middlemore Hospital.

IgA Nephropathy

The Align Study

Age ≥ 18
Diagnosed with IgA Nephropathy
On a stable dose of an ACE inhibitor or ARB/unable to tolerate this therapy

See if you qualify

Respiratory

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Respiratory

Severe Asthma

Choosebetweenamab

Aged >12 years
Diagnosed and confirmed with asthma
Have had asthma for at least 1 year
Evidence of past or current atopy
Total serum human IgE ≥ 30 IU/ml
Eosinophil count ≥ 300 cells microliter in last 12 months or ≥150 cells per microlitre while on oral corticosteroids in the last 12 months

By Specialist Referral
Trial for eligible patients at Middlemore Hospital.

Bronchiectasis

ASPEN

Aged 18-85, diagnosed non-cystic fibrosis bronchiectasis, two or more exacerbations in the past 12 months.

See if you qualify

Chronic Obstructive Pulmonary Disease (COPD)

ALIENTO

Aged between 40 and 90 years.
Confirmed COPD diagnosis.
Have a history of frequent exacerbations (2 or more exacerbation in a 12 month period).

See if you qualify

Bronchiectasis

Resveratrol

Age ≥ 18
Confirmed diagnosis of bronchiectasis within 5 years
Pulmonary exacerbation requiring antibiotics in the past 12 months

See if you qualify

Rheumatology

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Rheumatology

Systemic Lupus Erythematosus

ALLEGORY

Age 18 - 75
Diagnosed systemic lupus erythematosus (SLE)
Must be receiving one or more standard therapies for SLE at a stable dose

By Specialist Referral
Ask you Rheumatologist if this is right for you.

Giant Cell Arthritis

Select - GCA (M16-852)

Age ≥ 50
Diagnosed giant cell arthritis
Headache, jaw pain, vision loss
Shoulder and/or hip pain

See if you qualify

Spinal Unit

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Spinal Unit

Spinal cord injury

AFES

Age >18
Acute tetraplegic patients

By Specialist Referral
Trial for eligible patients with acute presentation at Middlemore Hospital.

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About Us

Middlemore Clinical Trials is a fully integrated research unit based at Middlemore Hospital in the heart of South Auckland, New Zealand.

We perform biopharma and medical device clinical trials in partnership with all hospital departments focusing on the diseases and long term health conditions that affect our diverse community.

Our Contacts

Phone: +64 9 270 9758
Email: info@mmclintrials.nz

Recruiting Trials

Clinical Lipidology

Familial Chylomicronemia Syndrome

Gastroenterology / Hepatology

Non-alcoholic Steatohepatitis (NASH)

Chronic Hepatitis B

Chronic Hepatitis B

Haematology

Multiple Myeloma

Multiple Myeloma

Myelodysplastic Syndrome

Myelofibrosis

Infectious Diseases and Vaccines

Staphylococcus Aureus Infection

Urinary Tract Infection

COVID-19 Infection

Oncology

Colorectal Adenoma

Paediatrics

Acute Lower Respiratory Infection (ALRI)

Plastics and Burns

Wound healing

Renal

End Stage Kidney Disease (ESKD)

IgA Nephropathy

Respiratory

Severe Asthma

Bronchiectasis

Chronic Obstructive Pulmonary Disease (COPD)

Bronchiectasis

Rheumatology

Systemic Lupus Erythematosus

Giant Cell Arthritis

Spinal Unit

Spinal cord injury

Participant Navigation

About Us

Our Contacts